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Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector.
Oligonucleotide Synthesis, Modification and Purification Services Market 2019 Glob.al Share, Trend, Segmentation and Forecast to 2030
Roots Analysis has done a detailed study on “Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2020-2030” covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Market Insights
- More than 80 companies currently claim to offer manufacturing related services, at different scales of operations, for a variety of oligonucleotide-based products
- A wide range of services related to the synthesis, modification and purification of oligonucleotides, are currently offered within a fragmented service provider landscape that is mostly concentrated in the developed geographies
- In order to cater to the growing needs of clients / sponsors, companies have established presence across different regions; the US and some European nations have emerged as current hubs for oligonucleotide production
- Players involved in this domain are steadily expanding their capabilities in order to enhance their respective service portfolios and thereby, achieve an edge over competing firms
- Service providers are actively investing in expansion projects to upgrade existing capabilities and capacity; several partnerships, mostly focused on offering manufacturing and supply services, have been forged
- Over the past few years, more than 270 trials of oligonucleotide-based interventions, across various phases of development and to treat a diverse range of diseases, have been registered across different centers worldwide
- Most of the global, annual oligonucleotide manufacturing capacity belongs to established service providers, accounting for over 80% of available capacity across various geographies
- The demand for manufacturing of oligonucleotide-based products is expected to increase in the coming years; we believe that the stakeholders may have to expand their respective capacities to ensure consistent supply
- We expect oligonucleotide-based drug developers to continue to outsource their manufacturing operations in the short to mid-term; service-based revenues are estimated to grow at an annualized rate of more than 10%
- In the long-term, the projected opportunity is anticipated to be well distributed across various therapeutic areas, scales of operation and across companies of different sizes
Table of Contents
- PREFACE
- Scope of the Report
- Research Methodology
- Chapter Outlines
- EXECUTIVE SUMMARY
- INTRODUCTION
- Context and Background
- Overview of Oligonucleotide-based Products
- Types of Oligonucleotides
- Antisense Oligonucleotides
- Aptamers
- miRNA
- shRNA
- siRNA
- Other Oligonucleotides
- Custom Synthesis of Oligonucleotides
- Process Development and Characterization
- Analytical Method Development
- Method Validation and Testing
- Quality Control and Quality Assurance
- Challenges Associated with Custom Synthesis of Oligonucleotides
- Chemical Modification of Oligonucleotides
- Backbone Modification
- Sugar Ring Modification
- Purification of Oligonucleotides
- Desalting
- Cartridge Purification
- Polyacrylamide Gel Electrophoresis (PAGE)
- High Performance Liquid Chromatography (HPLC)
- Outsourcing Oligonucleotide Manufacturing
- Need for Outsourcing
- Commonly Outsourced Operations
- Advantages of Outsourcing Manufacturing Operations
- Guidelines for Selecting a Service Provider
- Growth Drivers and Roadblocks to Oligonucleotide Manufacturing
- Recent Developments and Upcoming Trends
- MARKET LANDSCAPE: OLIGONUCLEOTIDE MANUFACTURERES (RESEARCH AND DIAGNOSTIC APPLICATIONS)
- Chapter Overview
- Oligonucleotide Manufacturers Focused on Research and Diagnostic Applications: Overall Market Landscape
- Analysis by Year of Establishment
- Analysis by Company Size
- Analysis by Scale of Operation
- Analysis by Geographical Location
- Analysis by Location of Manufacturing Facilities
- Analysis by Regulatory Accreditations / Certifications
- Analysis by Type of Oligonucleotide Manufactured
- Analysis by Type of Offering
- Analysis by Type of Manufacturing Service(s) Offered
- Analysis by Type of Modification(s) Offered
- Analysis by Type of Purification Method(s) Used
- Analysis by Compliance to cGMP Standards
- MARKET LANDSCAPE: OLIGONUCLEOTIDE MANUFACTURERES (THERAPEUTIC APPLICATIONS)
- Chapter Overview
- Oligonucleotide Manufacturers Focused on Therapeutic Applications: Overall Market Landscape
- Analysis by Year of Establishment
- Analysis by Company Size
- Analysis by Scale of Operation
- Analysis by Geographical Location
- Analysis by Location of Manufacturing Facilities
- Analysis by Regulatory Accreditations / Certifications
- Analysis by Type of Oligonucleotide Manufactured
- Analysis by Type of Offering
- Analysis by Type of Manufacturing Service(s) Offered
- Analysis by Type of Modification(s) Offered
- Analysis by Type of Purification Method(s) Used
- Analysis by Compliance to cGMP Standards
- COMPANY COMPETITIVENESS ANALYSIS: OLIGONUCLEOTIDE MANUFACTURES (RESEARCH AND DIAGNOSTIC APPLICATIONS)
- Chapter Overview
- Key Assumptions and Methodology
- Company Competitiveness Analysis: Oligonucleotide Manufacturers Focused on Research and Diagnostic Applications
- Oligonucleotide Manufacturers in North America
- Oligonucleotide Manufacturers in Europe
- Oligonucleotide Manufacturers in Asia-Pacific
- COMPANY COMPETITIVENESS ANALYSIS: OLIGONUCLEOTIDE MANUFACTURERS (THERAPEUTIC APPLICATIONS)
- Chapter Overview
- Key Assumptions and Methodology
- Company Competitiveness Analysis: Oligonucleotide Manufacturers Focused on Therapeutic Applications
- Oligonucleotide Manufacturers in North America
- Oligonucleotide Manufacturers in Europe
- Oligonucleotide Manufacturers in Asia-Pacific
- COMPANY PROFILES: OLIGONUCLEOTIDE MANUFACTURERS (RESEARCH AND DIAGNOSTIC APPLICATIONS)
- Chapter Overview
- Ajinomoto Bio-Pharma Services
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- Integrated DNA Technologies
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- Kaneka Eurogentec
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- LGC Biosearch Technologies
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- Microsynth
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- Sigma Aldrich
- Company Overview
- Financial Information
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- Thermo Fisher Scientific
- Company Overview
- Financial Information
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- COMPANY PROFILES: OLIGONUCLEOTIDE MANUFACTURERS (THERAPEUTIC APPLICATIONS)
- Chapter Overview
- Agilent Technologies
- Company Overview
- Financial Information
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- BioSpring
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- CordenPharma
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- Nitto Denko Avecia
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- TriLink Biotechnologies
- Company Overview
- Service Portfolio
- Manufacturing Facilities and Capabilities
- Recent Developments and Future Outlook
- PARTNERSHIPS AND COLLABORATIONS
- Chapter Overview
- Partnership Models
- Oligonucleotide Manufacturers: Recent Partnerships and Collaborations
- Analysis by Year of Partnership
- Analysis by Type of Partnership
- Analysis by Type of Partner
- Most Active Players: Analysis by Number of Partnerships
- Geographical Analysis
- Most Active Players: Geographical Distribution by Number of Partnerships
- Intercontinental and Intracontinental Agreements
- RECENT EXPANSIONS
- Chapter Overview
- Oligonucleotide Manufacturers: Recent Expansions
- Analysis by Year of Expansion
- Analysis by Type of Expansion
- Analysis by Application
- Analysis by Location of Facility
- Analysis by Expanded Facility Area
- Analysis by Expanded Scale of Operation
11.3.7. Most Active Players: Analysis by Number of Expansions
11.3.8. Geographical Analysis
11.3.8.1. Continent-wise Distribution
11.3.8.2. Country-wise Distribution
- CLINICAL TRIAL ANALYSIS
- Chapter Overview
- Scope and Methodology
- Clinical Trial Analysis: Oligonucleotide-based Drug Products
- Analysis by Trial Registration Year
- Analysis by Phase of Development
- Analysis by Type of Oligonucleotide
- Analysis by Type of Oligonucleotide and Phase of Development
- Analysis by Trial Recruitment Status
- Analysis by Trial Focus Area
- Analysis by Target Therapeutic Area
- Geographical Analysis by Number of Clinical Trials
- Geographical Analysis by Enrolled Patient Population
- Analysis by Type of Sponsor / Collaborator
- Most Active Players: Analysis by Number of Registered Trials
- CAPACITY ANALYSIS
- Chapter Overview
- Key Assumptions and Methodology
- Oligonucleotide Manufacturers: Global, Annual Capacity
- Analysis by Size of Manufacturer
- Analysis by Scale of Operation
- Analysis by Location of Manufacturing Facility
- DEMAND ANALYSIS
- Chapter Overview
- Key Assumptions and Methodology
- Global Demand for Oligonucleotide Manufacturing
- Global Commercial Demand for Oligonucleotide Manufacturing
- Analysis by Type of Oligonucleotide
- Analysis by Target Therapeutic Area
- Analysis by Geography
- Global Clinical Demand for Oligonucleotide Manufacturing
- Analysis by Type of Oligonucleotide
- Analysis by Phase of Development
- Analysis by Target Therapeutic Area
- Analysis by Geography
- Demand and Supply Analysis
- Demand and Supply Analysis (Scenario 1)
- Demand and Supply Analysis (Scenario 2)
- Demand and Supply Analysis (Scenario 3)
- Global Commercial Demand for Oligonucleotide Manufacturing
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/oligonucleotide-synthesis/304.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Neoantigen Targeted Therapies Market 2019 Glob.al Share, Trend, Segmentation and Forecast to 2030
Roots Analysis has done a detailed study on Neoantigen Targeted Therapies, 2019-2030, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Market Insights
• Presently, over 150 neoantigen targeted therapies are being evaluated for advanced cancer indications and are designed for delivery via different routes of administration
• Several molecules are in early stages of clinical development; based on delivery strategies, variety of vaccines and immunotherapies have been established for targeting personalized and shared antigens
• Over the years, more than 6,000 patents related to neoantigens and affiliated therapies have been granted / filed; this is indicative of the heightened pace of research in this field
• Both industry and academic players are contributing to the innovation, which is evident across published scientific literature focused on multiple targeted therapies for a myriad of cancer indications
• Several investors, having realized the untapped opportunity within this emerging segment of cancer immunotherapy, have invested over USD 7 billion across 150 instances in the period between 2014 and 2019
• The increasing traction in this field is also reflected in the partnership activity; deals inked in the recent past focused on a diverse range of therapies, involving both international and indigenous stakeholders
• The market will receive the required impetus after approval of the first neoantigen targeted therapy; the future growth is likely to be driven by the successful clinical outcomes of the late-stage molecules
• In fact, opinions from industry experts confirm the vast potential of this segment of cancer immunotherapy, capable of targeting personalized / off-the-shelf tumour antigens with multiple types of vaccines and therapies providers
Table of Contents
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Concept of Immunotherapy
3.3. History of Cancer Immunotherapy
3.4. Limitations of Cancer Immunotherapy
3.5. Targeting Tumor-Specific Neoantigens
3.5.1. Types of Neoantigens
3.5.2. Role of Neoantigens in Cancer Immunotherapy
3.5.3. Neoantigen Targeted Therapies
3.5.3.1. Identification and Selection of Neoantigens
3.5.3.2. Delivery of Neoantigen Targeted Therapies
3.6. Key Challenges and Future Perspectives
4. MARKET OVERVIEW
4.1. Chapter Overview
4.2. Neoantigen Targeted Therapies: Marketed and Development Pipeline
4.3. Neoantigen Targeted Therapies: Pipeline Analysis
4.3.1. Analysis by Phase of Development
4.3.2. Analysis by Type of Molecule
4.3.3. Analysis by Type of Immunotherapy
4.3.4. Analysis by Type of Therapy
4.3.5. Analysis by Route of Administration
4.3.6. Analysis by Target Disease Indication
4.3.7. Analysis by Type of Neoantigen
4.3.8. Analysis by Line of Therapy
4.3.9. Funnel Analysis: Analysis by Phase of Development, Type of Immunotherapy and Type of Therapy
4.3.10. Heptagon Representation: Analysis by Phase of Development and Route of Administration
4.4. Neoantigen Targeted Therapies: List of Drug Developers
4.4.1. Analysis by Year of Establishment
4.4.2. Analysis by Company Size and Geographical Location
4.4.3. Leading Developers
4.4.4. Analysis by Geography
4.5 Grid Analysis: Analysis by Target Disease Indication, Company Size and Location
5. COMPANY PROFILES: NEOANTIGEN TARGETED THERAPIES
5.1. Chapter Overview
5.2. Bavarian Nordic
5.2.1. Company Overview
5.2.2. Financial Information
5.2.3. Neoantigen Targeted Therapies Portfolio
5.2.4. Recent Collaborations
5.2.5. Future Outlook
5.3. Genocea Biosciences
5.3.1. Company Overview
5.3.2. Financial Information
5.3.3. Neoantigen Targeted Therapies Portfolio
5.3.4. Recent Collaborations
5.3.5. Future Outlook
5.4. Gradalis
5.4.1. Company Overview
5.4.2. Neoantigen Targeted Therapies Portfolio
5.4.3. Recent Collaborations
5.4.4. Future Outlook
5.5. Immunicum
5.5.1. Company Overview
5.5.2. Financial Information
5.5.3. Neoantigen Targeted Therapies Portfolio
5.5.4. Recent Collaborations
5.5.5. Future Outlook
5.6. Immunovative Therapies
5.6.1. Company Overview
5.6.2. Neoantigen Targeted Therapies Portfolio
5.6.3. Recent Collaborations
5.6.4. Future Outlook
5.7. Iovance Biotherapeutics
5.7.1. Company Overview
5.7.2. Financial Information
5.7.3. Neoantigen Targeted Therapies Portfolio
5.7.4. Recent Collaborations
5.7.5. Future Outlook
5.8. MediGene
5.8.1. Company Overview
5.8.2. Financial Information
5.8.3. Neoantigen Targeted Therapies Portfolio
5.8.4. Recent Collaborations
5.8.5. Future Outlook
5.9. Neon Therapeutics
5.9.1. Company Overview
5.9.2. Financial Information
5.9.3. Neoantigen Targeted Therapies Portfolio
5.9.4. Recent Collaborations
5.9.5. Future Outlook
6. PUBLICATION ANALYSIS
6.1. Chapter Overview
6.2. Methodology
6.3. Neoantigen Targeted Therapies: List of Publications
6.3.1. Analysis by Year of Publication
6.3.2. Analysis by Type of Study
6.3.3. Analysis by Study Objective
6.3.4. Analysis by Affiliated Therapies
6.3.5. Analysis by Target Disease Indication
6.3.6. Key Journals: Analysis by Number of Publications
7. PATENT ANALYSIS
7.1. Chapter Overview
7.2. Scope and Methodology
7.3. Neoantigen Targeted Therapies: Patent Analysis
7.3.1. Analysis by Publication Year
7.3.2. Analysis by Geographical Location
7.3.3. Analysis by CPC Classifications
7.3.4. Analysis by Type of Industry
7.3.5. Emerging Focus Areas
7.3.6. Leading Players: Analysis by Number of Patents
7.4. Neoantigen Targeted Therapies: Patent Benchmarking Analysis
7.4.1. Analysis by Patent Characteristics
7.5. Neoantigen Targeted Therapies: Patent Valuation Analysis
8. PARTNERSHIPS AND COLLABORATIONS
8.1. Chapter Overview
8.2. Partnership Models
8.3. Neoantigen Targeted Therapies: List of Partnerships and Collaborations
8.3.1. Analysis by Year of Partnership
8.3.2. Analysis by Type of Partnership
8.3.3. Analysis by Type of Immunotherapy
8.3.4. Analysis by Type of Partnership and Type of Product
8.3.5. Analysis by Type of Partnership and Target Disease Indication
8.3.6. Regional Analysis
8.3.7. Most Active Players: Analysis by Number of Partnerships
9. FUNDING AND INVESTMENT ANALYSIS
9.1. Chapter Overview
9.2. Types of Funding
9.3. Neoantigen Targeted Therapies: Funding and Investment Analysis
9.3.1. Analysis by Number of Instances
9.3.2. Analysis by Amount Invested
9.3.3. Analysis by Type of Funding
9.3.4. Analysis by Amount Invested across Different Types of Therapies
9.3.5. Analysis by Amount Invested across Different Types of Indications
9.3.4. Analysis by Geography
9.3.6. Most Active Players: Analysis by Amount of Funding
9.3.7. Most Active Investors: Analysis by Number of Instances
9.4. Concluding Remarks
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/neoantigen-targeted-therapies-market-2019-2030/257.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
In Silico Drug Discovery Services Market Report – Industry Size, Share, Trends, Growth and Forecast Till 2030
Roots Analysis has done a detailed study on “In Silico / Computer-Aided Drug Discovery Services Market: Focus on Large Molecules (Antibodies, Proteins, Peptides, Nucleic Acid, Gene Therapy and Vectors), 2020-2030 (Including Structure Based Drug Discovery, Fragment Based Drug Discovery, Ligand Based Drug Discovery, Target Based Drug Discovery / Multi-Target Drug Design, Interface Based Drug Discovery, Approaches)” covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Market Insights
• Over 90 firms are actively involved in providing in silico services for drug discovery of different types of biologics; of these, over 30 players claim to have the capabilities to offer services for all steps of discovery
• Majority of the companies offer structure-based drug design focused on early stage drug discovery of a range of large molecules, including antibodies, proteins and peptides
• Featuring the presence of small-mid sized firms, the in silico service provider landscape is well-distributed across various regions; these players have adopted various business models to cater to the evolving needs of the clients
• Several players involved in this domain n are steadily expanding their capabilities in order to enhance their respective in silico-based service portfolios and maintain a competitive edge in this industry
• The integration of novel computational techniques, such as artificial intelligence and cloud-based platforms, with in silico approaches is likely to revolutionize the overall drug discovery process
• Service providers are adopting various business strategies in order to continue providing significant cost saving advantages, along with expediting discovery timelines and improving product success
• Driven by the growing demand for effective therapeutics and increase in drug discovery efforts of various biologics across a wide range of therapeutic areas, the market is expected to witness sustained growth in future
• In the long-term, the projected opportunity is anticipated to be well distributed across various geographies, type of sponsors and sizes of in silico service providers
Table of Contents
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Drug Discovery and Development Timelines
3.3. Overview of In Silico Drug Discovery Tools
3.3.1. Historical Evolution of the In Silico Approach
3.3.2. Comparison of Traditional Drug Discovery Approaches and In Silico / Computer Aided Methods
3.3.3. In Silico / Computed Aided Approaches for Drug Design and Development
3.4. Applications of In Silico Tools in the Drug Discovery Process
3.4.1. Target Identification
3.4.1.1. Chemoinformatics-based Tools
3.4.1.2. Network-based Drug Discovery
3.4.1.3. Computational Platforms and Interaction Repositories
3.4.2. Target Validation
3.4.3. Hit Generation
3.4.3.1. High-Throughput Screening
3.4.3.2. Fragment Based Screening
3.4.3.3. Virtual Screening
3.4.4. Hit-to-Lead
3.4.4.1. Pharmacodynamics and Pharmacokinetics Modeling
3.4.4.2. Other Novel Approaches
3.4.5. Lead Optimization
3.4.5.1. Pharmacophore Modeling
3.4.5.2. Docking
3.4.5.3. Structure Activity Relationships (SAR) / Quantitative Structure Activity Relationship (QSAR)
3.4.5.4. Molecular Modeling
3.5. Advantages of using In Silico Tools for Drug Discovery Operations
3.6. Challenges Associated with Conducting In Silico Drug Discovery Operations In-house
3.7. Anticipated Rise in Outsourcing In Silico Drug Discovery Operations
3.8. Concluding Remarks
4. MARKET LANDSCAPE
4.1. Chapter Overview
4.2. In Silico Drug Discovery Services for Large Molecules: List of Industry Players
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis by Company Size
4.2.3. Analysis by Location of Headquarters
4.2.4. Analysis by Company Size and Location of Headquarters
4.2.5. Analysis by Type of Business Model
4.2.6. Analysis by Drug Discovery Steps
4.2.7. Analysis by Type of Large Molecule
4.2.7.1. Analysis by Type of Antibody
4.2.7.2. Analysis by Type of Protein
4.2.8. Analysis by Type of In Silico Approach Used
4.2.9. Analysis by Types of In Silico Services Offered
4.2.10. Analysis by Type of Clientele
4.3. In Silico Drug Discovery Services: List of Software / Technologies
5. KEY INSIGHTS
5.1. Chapter Overview
5.2. Logo Landscape: Analysis by Company Size and Location of Headquarters
5.3. Tree Map Representation: Analysis by Company Size and Drug Discovery Steps
5.4. World Map Representation: Regional Analysis of Outsourcing Activity
5.5. Grid Representation: Analysis by Type of Large Molecule, In Silico Approach Used and Type of Clientele
6. COMPANY PROFILES
6.1. Chapter Overview
6.2. Key In Silico Service Providers Based in North America
6.2.1. BioDuro
6.2.1.1. Company Overview
6.2.1.2. Funding and Investment Information
6.2.1.3. In Silico-based Service Portfolio
6.2.1.4. Recent Developments and Future Outlook
6.2.1.5. Peer Group Benchmark Comparison
6.2.2. Creative Biostructure
6.2.2.1. Company Overview
6.2.2.2. Funding and Investment Information
6.2.2.3. In Silico-based Service Portfolio
6.2.2.4. Recent Developments and Future Outlook
6.2.2.5. Peer Group Benchmark Comparison
6.2.3. GenScript
6.2.3.1. Company Overview
6.2.3.2. Funding and Investment Information
6.2.3.3. In Silico-based Service Portfolio
6.2.3.4. Recent Developments and Future Outlook
6.2.3.5. Peer Group Benchmark Comparison
6.2.4. LakePharma
6.2.4.1. Company Overview
6.2.4.2. Funding and Investment Information
6.2.4.3. In Silico-based Service Portfolio
6.2.4.4. Recent Developments and Future Outlook
6.2.4.5. Peer Group Benchmark Comparison
6.3. Leading Players Based in Europe
6.3.1. Abzena
6.3.1.1. Company Overview
6.3.1.2. Funding and Investment Information
6.3.1.3. In Silico-based Service Portfolio
6.3.1.4. Recent Developments and Future Outlook
6.3.1.5. Peer Group Benchmark Comparison
6.3.2. BioNTech
6.3.2.1. Company Overview
6.3.2.2. Funding and Investment Information
6.3.2.3. Recent Developments and Future Outlook
6.3.2.4. Peer Group Benchmark Comparison
6.3.3. Sygnature Discovery
6.3.3.1. Company Overview
6.3.3.2. Funding and Investment Information
6.3.3.3. In Silico-based Service Portfolio
6.3.3.4. Recent Developments and Future Outlook
6.3.3.5. Peer Group Benchmark Comparison
6.4. Leading Players Based in Asia-Pacific
6.4.1. ChemPartner
6.4.1.1. Company Overview
6.4.1.2. In Silico-based Service Portfolio
6.4.1.3. Recent Developments and Future Outlook
6.4.1.4. Peer Group Benchmark Comparison
6.4.2. Sundia MediTech
6.4.2.1. Company Overview
6.4.2.2. Funding and Investment Information
6.4.2.3. In Silico-based Service Portfolio
6.4.2.4. Recent Development and Future Outlook
6.4.2.5. Peer Group Benchmark Comparison
6.4.3. Viva Biotech
6.4.3.1. Company Overview
6.4.3.2. Funding and Investment Information
6.4.3.3. In Silico-based Service Portfolio
6.4.3.4. Recent Development and Future Outlook
6.4.3.5. Peer Group Benchmark Comparison
7. COMPANY COMPETITIVENESS ANALYSIS
7.1. Chapter Overview
7.2. Key Parameters
7.3. Methodology
7.4. Company Competitiveness Analysis: In Silico Drug Discovery Service Providers in North America
7.5. Company Competitiveness Analysis: In Silico Drug Discovery Service Providers in Europe
7.6. Company Competitiveness Analysis: In Silico Drug Discovery Service Providers in Asia-Pacific and Rest of the World
8. KEY OPPORTUNITY AREAS
8.1. Chapter Overview
8.2. Key Assumptions and Parameters
8.3. Methodology
8.4. Antibodies
8.4.1. Developer Landscape
8.4.1.1. Number of Pipeline Molecules
8.4.1.2. Affiliated Market Size and Growth Rate
8.4.2. In Silico Service Providers for Antibodies: 3D Bubble Analysis Based on Number of Drug Discovery Steps, Strength of Service Portfolio and Company Size
8.5. Peptides
8.5.1. Developer Landscape
8.5.1.1. Number of Pipeline Molecules
8.5.1.2. Affiliated Market Size and Growth Rate
8.5.2. In Silico Service Providers for Peptides: 3D Bubble Analysis Based on Number of Drug Discovery Steps, Strength of Service Portfolio and Company Size
8.6. Proteins
8.6.1. Developer Landscape
8.6.1.1. Number of Pipeline Molecules
8.6.1.2. Affiliated Market Size and Growth Rate
8.6.2. In Silico Service Providers for Proteins: 3D Bubble Analysis Based on Number of Drug Discovery Steps, Strength of Service Portfolio and Company Size
8.7. Other Advanced Therapies
8.7.1 Developer Landscape
8.7.1.1 Number of Pipeline Molecules
8.7.1.2 Affiliated Market Size and Growth Rate
8.7.2. In Silico Service Providers for Vectors: 3D Bubble Analysis Based on Number of Drug Discovery Steps, Strength of Service Portfolio and Company Size
9. EMERGING BUSINESS MODELS AND STRATEGIES
9.1. Chapter Overview
9.2. Key Assumptions and Methodology
9.3. In Silico Service Providers: Analysis by Number of Large Molecules and Drug Discovery Steps Covered
9.3.1. Strategies for Short Term Success
9.3.2. Strategies for Long Term Success
9.4. Concluding Remarks
10. CASE STUDY: COMPARISON OF DRUG DISCOVERY PROCESSES OF SMALL MOLECULES AND LARGE MOLECULES
10.1. Chapter Overview
10.2. Small Molecule and Large Molecule Drugs / Therapies
10.2.1. Comparison of Key Specifications
10.2.2. Comparison of Manufacturing Processes
10.2.3. Comparison of Drug Discovery Processes
10.3. Approaches to Improve Discovery Process of Large Molecules
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/in-silico-drug-discovery/298.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
Human Microbiome-based Products Market Headed for Growth and Global Expansion by 2030
Roots Analysis has announced the addition of “Human Microbiome Market, 2019-2030” report to its list of offerings.
Key Market Insights
- Presently, 260 drug candidates are being evaluated in clinical / preclinical stages for the treatment of a wide variety of disease indications; the US has emerged as the major hub for microbiome-based research
- The pipeline features both prebiotic and probiotic drugs, being evaluated across different stages of development; majority of these products are designed for administration via non-invasive routes, such as oral and topical
- Microbiome therapeutics have demonstrated the potential to target a range of therapeutic areas; digestive and GI disorders, oncology, infectious diseases, and metabolic disorders are amongst the prime focus areas
- Over 10 microbiome-focused disease diagnosis tests are already available in the market; several companies claim to have initiatives in this domain based on different sample types and therapeutic areas
- Presently, FMTs are the only commercially available microbiome products for the treatment of recurrent CDIs; in fact, several trials evaluating FMTs, sponsored by non-industry players, have been registered in the past decade
- Over time, well funded start-ups have initiated product development programs, having invested significant time and effort to explore the applicability of microbiome therapeutics across various indications
- Several big pharmaceutical players have partnered with smaller and dedicated microbiome-based therapy / diagnostic developers in order to expand their respective capabilities in this upcoming field of pharmacology
- Contract service providers have become an integral part of microbiome supply chain owing to their technical expertise and ability to overcome existing challenges related to both R&D and production
- Prevalent trends indicate that microbiome drugs and diagnostics market is poised to grow significantly; the forecasted opportunity is anticipated to be distributed across different target indications and regions
- Microbiome therapeutic developers are expected to witness significant momentum, in terms of revenues generation, as multiple late stage molecules for the treatment of different clinical conditions get commercialized
Table of Contents
- PREFACE
- Scope of the Report
- Research Methodology
- Chapter Outlines
- EXECUTIVE SUMMARY
- INTRODUCTION
- Chapter Overview
- Concept of Microbiota and Microbiome
- Discovery of the Human Microbiome
- Functions of the Human Microbiome
- Overview of Gut Flora
- Role of Gut Flora in Healthy Individuals
- Factors Affecting Gut Flora
- Antibiotic Consumption
- Age and Pregnancy
- Mode of Childbirth
- Type of Feeding
- Antibiotic Consumption by Mother
- Stress-related Factors
- Dietary Factors
- Impact of Lifestyle
- The Microbiome and Disease
- Cancer
- Inflammatory Bowel Disease (IBD)
- Obesity
- Parkinson’s Disease
- Type-II Diabetes
- Other Disease Indications
- Impact of Microbiota on Drug Pharmacokinetics
- Impact of Microbiota on Therapeutic Outcomes
- Microbiome Therapeutics
- Probiotics
- Beneficial Bacterial Strains
- Lactobacilli
- Bifidobacteria
- Others
- Key Therapeutic Areas
- Antibiotic-Associated Diarrhea (AAD)
- Bacterial Vaginosis
- High Blood Pressure
- Hypercholesterolemia
- Infectious Childhood Diarrhea (ICD)
- Inflammatory Bowel Disease (IBD)
- Lactose Intolerance
- Vitamin Production
- Weight Management
- Side Effects of Probiotics
- Beneficial Bacterial Strains
- Prebiotics
- Sources of Prebiotics
- Types of Prebiotics
- Fructo-Oligosaccharides (FOS)
- Galacto-Oligosaccharides (GOS)
- Inulin
- Key Therapeutic Areas
- Antibiotic Associated Diarrhea (AAD)
- Constipation
- Gastrointestinal Disorders
- Dysbiosis
- Side Effects of Prebiotics
- The Human Microbiome Project (HMP)
- Project Approach
- Project Initiatives
- Project Achievements
- Regulatory Guidelines for Live Biotherapeutic Products (LBPs)
- Key Challenges in the Development of Microbiome Therapeutics
- Future Perspectives
- Probiotics
- MICROBIOME THERAPEUTICS: MARKET LANDSCAPE
- Chapter Overview
- Microbiome Therapeutics: Clinical Pipeline
- Analysis by Phase of Development
- Analysis by Type of Molecule
- Analysis by Type of Therapy
- Analysis by Target Indication
- Analysis by Therapeutic Area
- Analysis by Dosing Frequency
- Analysis by Route of Administration
- Analysis by Drug Formulation
- Microbiome Therapeutics: Early-Stage Pipeline
- Analysis by Phase of Development
- Analysis by Type of Molecule
- Analysis by Type of Therapy
- Analysis by Target Indication
- Analysis by Therapeutic Area
- Microbiome Therapeutics: List of Drug Developers
- Analysis by Year of Establishment
- Analysis by Location of Headquarters
- Analysis by Company Size
- Analysis by Company Size and Location of Headquarters
- Leading Drug Developers: Analysis by Number of Microbiome Therapeutics
- Grid Analysis: Microbiome and Key Therapeutic Areas
- Microbiome Therapeutics: List of Discontinued Drugs
- Emerging Role of Microbiome in Gut-Brain Axis
- Microbiome Therapeutics: List of Technology Platforms
- COMPANY AND DRUG PROFILES
- Chapter Overview
- 4D Pharma
- Company Overview
- Microbiome-based Product Portfolio
- Blautix®
- Drug Overview
- Current Status of Development
- Clinical Studies
- Clinical Trial End-Point Analysis
- Recent Developments and Future Outlook
- Blautix®
- Armata Pharmaceuticals
- Company Overview
- Microbiome-Based Product Portfolio
- C16G2
- Drug Overview
- Current Status of Development
- Clinical Studies
- Clinical Trial End-Point Analysis
- Recent Developments and Future Outlook
- C16G2
- Evelo Biosciences
- Company Overview
- Microbiome-Based Product Portfolio
- EDP1503
- Drug Overview
- Current Status of Development
- Clinical Studies
- Clinical Trial End-Point Analysis
- Recent Developments and Future Outlook
- EDP1503
- Rebiotix (Acquired by Ferring Pharmaceuticals)
- Company Overview
- Financial Information
- Microbiome-Based Product Portfolio
- RBX2660
- Drug Overview
- Current Status of Development
- Clinical Studies
- Clinical Trial End-Point Analysis
- Recent Developments and Future Outlook
- RBX2660
- Seres Therapeutics
- Company Overview
- Financial Information
- Microbiome-Based Product Portfolio
- SER-109
- Drug Overview
- Current Status of Development
- Clinical Studies
- Clinical Trial End-Point Analysis
- SER-287
- Current Status of Development
- Clinical Studies
- Clinical Trial End-Point Analysis
- Recent Developments and Future Outlook
- SER-109
- Vedanta Biosciences
- Company Overview
- Microbiome-Based Product Portfolio
- VE303
- Drug Overview
- Current Status of Development
- Clinical Studies
- VE303
5.7.3.1.4. Clinical Trial End-Point Analysis
- Recent Developments and Future Outlook
- MICROBIOME DIAGNOSTICS: MARKET LANDSCAPE
- Chapter Overview
- Overview of Microbiome Diagnostic Tests
- Microbiome Diagnostic Tests: Marketed and Under Development Products
- Analysis by Stage of Development
- Analysis by Type of Sample Required
- Analysis by Target Indication
- Analysis by Therapeutic Area
- Analysis by Purpose
- Microbiome Diagnostic Tests: List of Diagnostic Developers
- Analysis by Year of Establishment
- Analysis by Location of Headquarters
- Analysis by Company Size
- Analysis by Company Size and Location of Headquarters
- Leading Diagnostic Developers: Analysis by Number of Microbiome Diagnostics
- Profiles of Prominent Diagnostic Developers
- Enterome Bioscience
- Company Overview
- Service Portfolio
- Vaiomer
- Company Overview
- Service Portfolio
- Overview of Microbiome Screening / Profiling Tests
- List of Microbiome Screening / Profiling Tests
- List of Microbiome Screening / Profiling Test Developers
- Enterome Bioscience
- FECAL MICROBIOTA THERAPY (FMT)
- Chapter Overview
- Introduction to FMT
- Historical Overview
- FMT: Procedure and Clinical Relevance
- Donor Selection
- Administration Procedure
- Routes of Administration
- Consequences and Adverse Events
- Clinical Guidelines Associated with FMT
- Regulatory Guidelines Related to FMT
- Insurance Coverage for FMT
- FMT: Competitive Landscape
- Marketed / Development Pipeline (Industry Players)
- Analysis by Phase of Development
- Analysis by Therapeutic Area
- Analysis by Route of Administration
- List of Developers (Industry Players)
- Analysis by Year of Establishment
- Analysis by Location of Headquarters
- Analysis by Company Size
- Clinical Trial Analysis (Non-Industry Sponsored)
- Scope and Methodology
- List of Clinical Trials
- Analysis by Trial Registration Year
- Analysis by Trial Status
- Analysis by Phase of Development
- Analysis by Patients Enrolled
- Analysis of Number of Patients Enrolled by Trial Registration Year
- Analysis by Therapeutic Area
- Analysis by Popular Target Indications
- Analysis by Trial Registration Year and Recruitment Status
- Analysis by Study Design
- Leading Non-Industry Players: Analysis by Number of Trials
- Geographical Analysis by Number of Clinical Trials
- Geographical Analysis by Enrolled Patient Population
- Analysis by Type of Sponsor / Collaborator
- Analysis by Trial Focus
- Key Clinical Trials
- Stool Banks
- Introduction to Stool Banks
- List of Stool Banks
- Profiles of Prominent Stool Banks
- AdvancingBio
- Overview
- Fecal Microbiota Preparation
- Asia Microbiota bank
- Overview
- Fecal Microbiota Preparation
- Enterobiotix
- Overview
- Fecal Microbiota Preparation
- Flora Medicine
- Overview
- Fecal Microbiota Preparation
- OpenBiome
- Overview
- Fecal Microbiota Preparation
- AdvancingBio
- Marketed / Development Pipeline (Industry Players)
- ATTRACTIVENESS COMPETITIVENESS (AC) MATRIX
- Chapter Overview
- AC Matrix: An Overview
- Strong Opportunity Areas
- Average Opportunity Areas
- Weak Opportunity Areas
- AC Matrix: Analytical Methodology
- AC Matrix: Plotting the Information
- AC Matrix: Analyzing the Data
- Strong Opportunity Areas
- Average Opportunity Areas
- Weak Opportunity Areas
- MICROBIOME RELATED INITIATIVES OF BIG PHARMACEUTICAL PLAYERS
- Chapter Overview
- Scope and Methodology
- Initiatives of Big Pharmaceutical Players
- Analysis by Portfolio Diversity
- Analysis by Phase of Development
- Analysis by Type of Molecule
- Analysis by Type of Therapy
- Analysis by Diversity of Therapeutic Areas
- Benchmark Analysis of Big Pharmaceutical Players
- Spider Web Analysis: Company A
- Spider Web Analysis: Company B
- Spider Web Analysis: Company C
- Spider Web Analysis: Company D
- Spider Web Analysis: Company E
- Spider Web Analysis: Company F
- Spider Web Analysis: Company G
- Spider Web Analysis: Company H
- Spider Web Analysis: Company I
- Spider Web Analysis: Company J
- Spider Web Analysis: Company K
- START-UP HEALTH INDEXING
- Chapter Overview
- Scope and Methodology
- Benchmark Analysis of Start-ups
- Benchmark Analysis by Portfolio Diversity
- Benchmark Analysis by Phase of Development
- Benchmark Analysis by Diversity in Therapeutic Areas
- Benchmark Analysis by Funding Amount
- Benchmark Analysis by Number of Investors
- Benchmark Analysis by Progression in Funding
- Benchmark Analysis by Partnership Activity
- Benchmark Analysis by Patent Portfolio
- Start-up Health Indexing: Roots Analysis Perspective
- Short Profiles of Top Five Players
- Evelo Biosciences
- AOBiome Therapuetics
- SFA Therapeutics
- Azitra
- Axial Biotherapeutics
- KEY THERAPEUTIC AREAS
- Chapter Overview
- Metabolic Disorders
- Diabetes
- Disease Description
- Associated Health Risks / Complications
- Epidemiology
- Disease Diagnosis
- Current Treatment Options
- Insulin Therapies
- Non-Insulin Therapies
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Diabetes
- Lactose Intolerance
- Disease Description
- Diabetes
- Short Profiles of Top Five Players
1.2.2.2. Epidemiology
- Current Treatment Options
- Microbiome Therapeutics for Lactose Intolerance
- Nonalcoholic Steatohepatitis (NASH)
- Disease Description
- Epidemiology
- Current Treatment Options
- Microbiome Therapeutics for NASH
- Primary Hyperoxaluria
- Disease Description
- Epidemiology
- Current Treatment Options
- Microbiome Therapeutics for Primary Hyperoxaluria
- Obesity
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Obesity
- Digestive and Gastrointestinal Disorders
- Crohn’s Disease
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Crohn’s Disease
- Irritable Bowel Syndrome (IBS)
- Disease Description
- Epidemiology
- Current Treatment Options
- Microbiome Therapeutics for IBS
- Ulcerative Colitis
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Ulcerative Colitis
- Oncological Indications
- Colorectal Cancer
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatments
- Microbiome Therapeutics for Colorectal Cancer
- Lung Cancer
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Lung Cancer
- Dermatological Disorders
- Acne Vulgaris
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Acne Vulgaris
- Infectious Diseases
- Clostridium Difficile Infections (CDIs)
- Description
- Epidemiology
- Disease Diagnosis
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for CDI
- Bacterial Vaginosis
- Disease Description
- Epidemiology
- Current Treatment Options
- Side Effects of Current Treatment Options
- Microbiome Therapeutics for Bacterial Vaginosis
- FUNDING AND INVESTMENT ANALYSIS
- Chapter Overview
- Types of Funding
- Microbiome Therapeutics and Diagnostics: List of Funding and Investments
- Analysis by Number of Instances
- Analysis by Amount Invested
- Analysis by Type of Funding
- Analysis by Type of Company
- Analysis by Purpose of Funding
- Analysis by Type of Molecule
- Analysis by Target Indication
- Analysis by Therapeutic Area
- Analysis by Geography
- Most Active Players
- Most Active Investors
- Analysis by Type of Investors
- Analysis by Location of Investors
- Concluding Remarks
- CONTRACT SERVICES FOR MICROBIOME THERAPEUTICS
- Chapter Overview
- Manufacturing Microbiome Therapeutics
- Key Steps Involved
- Associated Challenges
- Growing Demand for Contract Manufacturing Services
- Contract Manufacturing Organizations (CMOs)
- Introduction to Contract Manufacturing
- List of Organizations Offering Services for Microbiome Therapeutics
- In-House Manufacturers
- Introduction to In-House Manufacturing
- List of In-House Manufacturers
- Microbiome Therapeutics-related R&D
- Growing Demand for Contract Research Services
- Contract Research Organizations (CROs)
- Introduction to Contract Research
- List of Organizations Offering Services for Microbiome Therapeutics
- Key Considerations for Selecting a Suitable CMO / CRO Partner
- BIG DATA AND MICROBIOME THERAPEUTICS
- Chapter Overview
- Introduction to Big Data
- Internet of Things
- Growing Interest in Big Data: Google Trends Analysis
- Key Application Areas
- Big Data in Microbiome Research
- Microbiome Data and Personalized Medicine
- Microbiome-related Data Management Challenges
- National Microbiome Data Center
- Big Data Services for Microbiome Research: List of Companies
- Big Data Services for Microbiome Research: Profiles of Key Players
- Human Longevity
- Company Overview
- Technology and Service Portfolio
- Recent Developments
- Resilient Biotics
- Company Overview
- Technology and Service Portfolio
- Recent Developments
- Resphera Biosciences
- Company Overview
- Technology and Service Portfolio
- MICROBIOME THERAPEUTICS: MARKET FORECAST AND OPPORTUNITY ANALYSIS
- Chapter Overview
- Scope and Limitations
- Forecast Methodology
- Overall Microbiome Therapeutics Market, 2019-2030
- Microbiome Therapeutics Market: Distribution by Type of Therapy, 2025 and 2030
- Microbiome Therapeutics Market for Prescription Drugs, 2019-2030
- Microbiome Therapeutics Market for Prebiotic Drugs, 2019-2030
- Microbiome Therapeutics Market for Probiotic Drugs, 2019-2030
- Microbiome Therapeutics Market: Distribution by Type of Molecule, 2025 and 2030
- Microbiome Therapeutics Market for Small Molecules, 2019-2030
- Microbiome Therapeutics Market for Biologics, 2019-2030
- Microbiome Therapeutics Market: Distribution by Target Indication, 2025 and 2030
- Microbiome Therapeutics Market for Acne Vulgaris, 2019-2030
- Microbiome Therapeutics Market for Atopic Dermatitis, 2019-2030
- Microbiome Therapeutics Market for CDI, 2019-2030
- Microbiome Therapeutics Market for Crohn’s Disease, 2019-2030
- Microbiome Therapeutics Market for Dental Caries, 2019-2030
- Microbiome Therapeutics Market for Diabetes, 2019-2030
- Microbiome Therapeutics Market for IBS, 2019-2030
- Microbiome Therapeutics Market for Lactose Intolerance, 2019-2030
- Microbiome Therapeutics Market for Lung Cancer, 2019-2030
- Microbiome Therapeutics Market for NASH, 2019-2030
- Microbiome Therapeutics Market for Primary Hyperoxaluria, 2019-2030
- Microbiome Therapeutics Market for Psoriasis, 2019-2030
- Microbiome Therapeutics Market for Ulcerative Colitis, 2019-2030
- Microbiome Therapeutics Market: Distribution by Therapeutic Area, 2025 and 2030
- Microbiome Therapeutics Market for Autoimmune Disorders, 2019-2030
- Microbiome Therapeutics Market for Dental Disorders, 2019-2030
- Microbiome Therapeutics Market for Digestive and Gastrointestinal Disorders, 2019-2030
- Microbiome Therapeutics Market for Dermatological Disorders, 2019-2030
- Microbiome Therapeutics Market for Infectious Diseases, 2019-2030
- Microbiome Therapeutics Market for Metabolic Disorders, 2019-2030
- Microbiome Therapeutics Market for Oncology, 2019-2030
- Microbiome Therapeutics Market: Distribution by Key Geographical Regions, 2025 and 2030
- Microbiome Therapeutics Market in North America, 2019-2030
- Microbiome Therapeutics Market in Europe, 2019-2030
- Microbiome Therapeutics Market in Asia-Pacific and Rest of the World, 2019-2030
- Microbiome Therapeutics Market: Distribution by Leading Drug Developers, 2025 and 2030
- Microbiome Therapeutics Market: Distribution by Type of Therapy, 2025 and 2030
- Microbiome Therapeutics Market: Distribution by Leading Therapeutic Products, 2019-2030
- Human Longevity
- Clostridium Difficile Infections (CDIs)
- Acne Vulgaris
- Colorectal Cancer
- Crohn’s Disease
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https://www.rootsanalysis.com/reports/view_document/human-microbiome-market/281.html
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Ophthalmic Drugs Contract Manufacturing Market Research Report 2019-2030
Roots Analysis has done a detailed study on Ophthalmic Drugs Contract Manufacturing Market: Focus on Active Pharmaceutical Ingredients and Finished Dosage Forms (Ophthalmic Drops, Emulsions, Gels, Injections, Lotions, Ointments, Suspensions, and Tablets / Capsules), 2020-2030, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Market Insights
- Over 240 companies across the globe claim to have the required capabilities to offer variety of services on a contract basis, working at different scales of operation, for a wide range of ophthalmic APIs and drug FDFs
- The market is fragmented, featuring the presence of both established players and small firms based in different geographies that claim to be capable of manufacturing ophthalmic products
- Presently, majority of the CMOs are offering services for ophthalmic drug FDFs packaged in a variety of formats; popular types of containers include glass / plastic bottles, ointment tubes and ampoules / vials
- In order to acquire competencies across the supply chain and cater to evolving needs of sponsors, companies have established presence across different regions, having been certified by various regulatory authorities
- Several players involved in this domain are steadily expanding their capabilities in order to enhance their respective service portfolios and maintain a competitive edge
- In the past few years, over 10,700 trials, enrolling approximately 4.6 million patients, suffering from a wide range of chronic eye conditions, have been registered across the globe by different sponsors
- Most of the installed, global ophthalmic drug manufacturing capacity belongs to larger and more established CMOs, accounting for over 80% of available capacity across various geographies
- The demand for manufacturing services for ophthalmic drug products is expected to increase in the coming years; we believe stakeholders may have to expand their respective capacities to ensure consistent supply
- We expect ophthalmic drug developers to continue to outsource their development and manufacturing operations in the short to mid-term, causing service-based revenues to grow at an annualized rate of over 8%
- In the long-term, the projected opportunity is anticipated to be well distributed across various packaging formats, scales of operation and sizes of contract service providers
- Eminent representatives from prominent ophthalmic drug contract manufacturing companies confirm the importance of outsourcing, highlighting prevalent and anticipated trends within this domain
Table of Contents
- PREFACE
- Scope of the Report
- Research Methodology
- Chapter Outlines
- EXECUTIVE SUMMARY
- INTRODUCTION
- Context and Background
- Introduction to Ophthalmology
- Chronic Eye Conditions and Associated Economic Burden
- Common Ophthalmic Drug Dosage Forms
- Types of Oral Drug Formulations
- Tablets
- Capsules
- Eye Supplements
- Types of Semi-solid Formulations
- Ointments
- Types of Oral Drug Formulations
3.5.2.2. Gels
3.5.2.3. Emulsions
- Types of Liquid Drug Formulations
- Solutions
- Suspensions
3.5.3.1. Sterile Injectables
- Intraocular Inserts
- Common Primary Packaging Formats for Ophthalmic Drugs
- Overview of Contract Manufacturing
- Outsourcing in the Ophthalmology Industry
- Need for Outsourcing
- Commonly Outsourced Operations
- Guidelines for Selecting a Contract Manufacturing Organization (CMO) Partner
- Advantages of Outsourcing Manufacturing Operations
- Challenges Associated with Ophthalmic Drugs Contract Manufacturing
- Growth Drivers and Roadblocks to Ophthalmic Drugs Contract Manufacturing
- Recent Developments and Upcoming Trends
- CURRENT MARKET LANDSCAPE
- Chapter Overview
- Ophthalmic Drug Contract Manufacturers: Overall Market Landscape
- Analysis by Year of Establishment
- Analysis by Company Size
- Analysis by Scale of Operation
- Analysis by Geographical Location
- Analysis by Location of Manufacturing Facilities
- Analysis by Type of Product
- Analysis by Type of FDF Manufactured
- Analysis by Type of Primary Packaging
- Analysis by Type of Service(s) Offered
- Analysis by Regulatory Accreditations / Certifications
- COMPANY COMPETITVENESS ANALYSIS
- Chapter Overview
- Key Assumptions and Methodology
- Competitiveness Analysis: Ophthalmic API Contract Manufacturers
- Ophthalmic API Contract Manufacturers in North America
- Ophthalmic API Contract Manufacturers in Europe
- Ophthalmic API Contract Manufacturers in Asia-Pacific
- Competitiveness Analysis: Ophthalmic Drug FDF Contract Manufacturers
- Ophthalmic Drug FDF Contract Manufacturers in North America
- Ophthalmic Drug FDF Contract Manufacturers in Europe
- Ophthalmic Drug FDF Contract Manufacturers in Asia-Pacific
- OPHTHALMIC DRUGS CONTERACT MANUFACTURING IN NORTH AMERICA: COMPANY PROFILES
- Chapter Overview
- Akorn
- Company Overview
- Financial Information
- Service Portfolio
- Recent Developments and Future Outlook
- Catalent
- Company Overview
- Financial Information
- Service Portfolio
6.2.4. Recent Developments and Future Outlook
- Cayman Chemical
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Pillar5 Pharma
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Sterling Pharmaceutical Services
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- OPHTHALMIC DRUGS CONTERACT MANUFACTURING IN EUROPE: COMPANY PROFILES
- Chapter Overview
- FARMIGEA
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Lomapharm
- Company Overview
- Service Portfolio
7.3.3 Recent Developments and Future Outlook
- Medichem
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Recipharm
- Company Overview
- Financial Information
- Service Portfolio
- Recent Developments and Future Outlook
- Salvat
- Company Overview
7.6.2 Service Portfolio
- Recent Developments and Future Outlook
- OPHTHALMIC DRUGS CONTERACT MANUFACTURING IN ASIA-PACIFIC: COMPANY PROFILES
- Chapter Overview
- Akums
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Bal Pharma
- Company Overview
- Financial Information
- Service Portfolio
8.2.4. Recent Developments and Future Outlook
- Entod Pharmaceuticals
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Glenmark Pharmaceuticals
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Indiana Ophthalmics
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- Sunways India
- Company Overview
- Service Portfolio
- Recent Developments and Future Outlook
- CLINICAL TRIAL ANALYSIS
- Chapter Overview
- Scope and Methodology
- Ophthalmic Drug Trial Analysis
- Analysis by Trial Registration Year
- Geographical Analysis by Number of Clinical Trials
- Geographical Analysis by Enrolled Patient Population
- Analysis by Phase of Development
- Analysis by Trial Recruitment Status
- Analysis by Type of Sponsor / Collaborator
- Most Active Players in Terms of Number of Registered Trials
- Analysis by Type of Intervention
- Analysis by Trial Focus
- Analysis by Target Indication
- Benchmark Analysis of Active Industry Players
- CAPACITY ANALYSIS
- Chapter Overview
- Key Assumptions and Methodology
- Ophthalmic API Contract Manufacturers: Global Production Capacity
- Analysis by Geography
- Overall Production Capacity in North America
- Overall Production Capacity in Europe
- Overall Production Capacity in Asia-Pacific
- Overall Production Capacity in Rest of the World
- Analysis by Scale of Operation
- Overall Clinical Scale Production Capacity
- Overall Commercial Scale Production Capacity
- Both Clinical and Commercial Scale Production Capacity
- Analysis by Company Size
- Overall Production Capacity of Small-sized Companies
- Overall Production Capacity of Mid-sized Companies
- Overall Production Capacity of Large Companies
- Overall Production Capacity of Very Large Companies
- Ophthalmic Drug FDF Contract Manufacturers: Global Production Capacity
- Analysis by Geography
- Overall Production Capacity in North America
- Overall Production Capacity in Europe
- Overall Production Capacity in Asia-Pacific
- Overall Production Capacity in Rest of the World
- Analysis by Scale of Operation
- Overall Clinical Scale Production Capacity
- Overall Commercial Scale Production Capacity
- Both Clinical and Commercial Scale Production Capacity
- Analysis by Company Size
- Overall Production Capacity of Small-sized Companies
- Overall Production Capacity of Mid-sized Companies
- Overall Production Capacity of Large Companies
- Overall Production Capacity of Very Large Companies
- Analysis by Type of Primary Packaging
- Overall Production Capacity of Ampoules / Vials
- Overall Production Capacity of Glass / Plastic Bottles
- Overall Production Capacity of Ointment Tubes
- Overall Production Capacity of Blister Packing
- Overall Production Capacity of Other Packaging Forms
- DEMAND ANALYSIS
- Chapter Overview
- Key Assumptions and Methodology
- Global Commercial Demand for Ophthalmic Drugs Contract Manufacturing
- Commercial Demand for Ophthalmic API Contract Manufacturing
- Analysis by Geography
- Analysis by Target Indication
- Commercial Demand for Ophthalmic Drug FDF Contract Manufacturing
- Analysis by Geography
- Analysis by Target Indication
- Analysis by Type of Primary Packaging
- Global Clinical Demand for Ophthalmic Drugs Contract Manufacturing
- Clinical Demand for Ophthalmic API Contract Manufacturing
- Analysis by Geography
- Analysis by Target Indication
- Clinical Demand for Ophthalmic Drug FDF Contract Manufacturing
- Analysis by Geography
- Analysis by Target Indication
- Analysis by Type of Primary Packaging
- Demand and Supply Analysis
- Clinical Demand for Ophthalmic API Contract Manufacturing
- MARKET FORECAST
- Chapter Overview
- Key Assumptions and Forecast Methodology
- Overall Ophthalmic Drugs Contract Manufacturing Market, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Type of Product
- Ophthalmic API Contract Manufacturing Market, 2020-2030
- Ophthalmic Drug FDF Contract Manufacturing Market, 2020-2030
- Ophthalmic Drug FDF Contract Manufacturing Market, 2020-2030: Distribution by Type of FDF Manufactured
- Ophthalmic Drugs Contract Manufacturing Market for Solids, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Semi-solids, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Liquids / Suspensions, 2020-2030
- Ophthalmic Drug FDF Contract Manufacturing Market, 2020-2030: Distribution by Type of Primary Packaging
- Ophthalmic Drugs Contract Manufacturing Market for Ampoules / Vials, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Glass / Plastic Bottles, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Ointment Tubes, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Blister Packing, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Other Packaging Forms, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Target Disease Indication
- Ophthalmic Drugs Contract Manufacturing Market for Age-related Macular Degeneration, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Dry Eye, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Glaucoma, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Other Eye Disorders, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Scale of Operation
- Ophthalmic Drugs Contract Manufacturing Market for Clinical Scale Operations, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Commercial Scale Operations, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Both Clinical and Commercial Scale Operations, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Size of Manufacturers
- Ophthalmic Drugs Contract Manufacturing Market for Small-sized Companies, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Mid-sized Companies, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Large Companies, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market for Very Large Companies, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Geographical Regions
- Ophthalmic Drugs Contract Manufacturing Market in North America, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in the US, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Canada, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Mexico, 2020-203
- Ophthalmic Drugs Contract Manufacturing Market in Europe, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in the UK, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Germany, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in France, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Spain, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Italy, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Rest of Europe, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Asia-Pacific, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in India, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in China, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Japan, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Australia, 2020-2030
- Ophthalmic Drugs Contract Manufacturing Market in Rest of Asia-Pacific, 2020-2030
- CASE STUDY: COMPARISON OF SMALL MOLECULE AND LARGE MOLECULE OPHTHALMIC DRUGS / THERAPIES
- Chapter Overview
- Small Molecule Drugs and Biologics in Ophthalmology
- Comparison of Strengths and Weakness of Small Molecules and Biologics
- Comparison of Key Specifications
- Comparison of Manufacturing Processes
- Comparison of Key Manufacturing-related Challenges
- SWOT ANALYSIS
- Chapter Overview
- Comparison of SWOT Factors
- SURVEY ANALYSIS
- Chapter Overview
- Overview of Respondents
- Seniority Level of Respondents
- Survey Insights
- Type of Product
- Type of Primary Packaging
- Scale of Operation
- Manufacturing Capacity
- Location of Manufacturing Facilities
- Regulatory Accreditations / Certifications of Manufacturing Facilities
- Extent of Outsourcing
- Current Market Opportunity
- EXECUTIVE INSIGHTS
- Chapter Overview
- Caplin Point Laboratories
- Company Snapshot
- Interview Transcript: Ashok Partheeban, Director, Latin American Operations and Vivek Partheeban, Chief Operating Officer
- Gland Pharma
- Company Snapshot
- Interview Transcript: Iranna Bavalatti, Head of Manufacturing Science and Technology
- Selvok Pharmaceutical
- Company Snapshot
- Interview Transcript: Rahul Gupta, Chief Executive Officer
- Phytex Australia
- Ophthalmic Drugs Contract Manufacturing Market in North America, 2020-2030
- Ophthalmic Drug FDF Contract Manufacturing Market, 2020-2030: Distribution by Type of FDF Manufactured
- Commercial Demand for Ophthalmic API Contract Manufacturing
- Analysis by Geography
- Analysis by Geography
16.4.1. Company Snapshot
16.4.2. Interview Transcript: Stuart Smith, Managing Director
- FUTURE GROWTH OPPORTUNITIES
- Chapter Overview
- Integration / Adoption of New and Innovative Technologies
- Capability and Expertise Expansions by CMOs
- Offshoring Outsourcing Activities
- Growing Investments in Existing Infrastructure
- Evolving Client / Sponsor and CMO / CDMO Relationships
- Challenges Faced by Both Sponsors and Service Providers
- Concerns Related to Single Use Systems
- Concerns Related to Capacity Fluctuations
- APPENDIX 1: LIST OF OPHTHALMIC MEDICAL DEVICE CONTRACT
- MANUFACTURERS
- APPENDIX 2: TABULATED DATA
- APPENDIX 3: LIST OF COMPANIES AND ORGANIZATIONS
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/ophthalmic-drugs-cmo/294.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Oligonucleotide Synthesis, Modification and Purification Services Market is Projected to Reach USD 5.8 billion by 2030
The applications of oligonucleotides are vast, even beyond the life science / pharma sector; however, owing to complexities associated with the synthesis and processing of these molecules, such operations are usually outsourced to capable CMOs
Roots Analysis is pleased to announce the publication of its recent study, titled, “Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2020-2030.”
The report features an extensive study of the current scenario and future potential of the custom synthesis, modification and purification services market for oligonucleotides, which are intended for research, diagnostic, and therapeutic applications. The study includes in-depth analyses, highlighting the capabilities of service providers engaged in this domain. In addition to other elements, it includes:
- A detailed review of the current status of the market with respect to oligonucleotide manufacturers focused on research and diagnostic, and therapeutic applications.
- A competitiveness analysis of prominent oligonucleotide manufacturers, featuring insightful pictorial summaries and representations.
- Elaborate profiles of key players that offer a diverse range of capabilities for custom synthesis, modification and purification of oligonucleotides.
- An analysis of the various partnerships pertaining to oligonucleotide manufacturing, which have been established in the recent past.
- An analysis of the various expansion initiatives undertaken by service providers engaged in this domain.
- A detailed analysis of completed, ongoing and planned clinical research studies of various oligonucleotide-based drug products.
- An estimate of the overall, annual capacity for manufacturing oligonucleotides based on data reported by industry stakeholders in the public domain.
- An informed estimate of the annual clinical and commercial demand for oligonucleotides.
- A discussion on affiliated trends, key drivers and challenges, under an elaborate SWOT framework.
- A survey analysis featuring inputs solicited from various experts who are directly / indirectly involved in providing custom synthesis, modification and purification services for oligonucleotides.
A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
Type of Manufacturing
- Custom Manufacturing
- Large-scale Manufacturing
Type of Oligonucleotides Manufactured
- Antisense Oligonucleotides
- miRNAs
- shRNAs
- siRNAs
- Other Oligonucleotides
Scale of Operation
- Clinical
- Commercial
Purpose of Production
- In-house
- Outsourced
Target Therapeutic Area
- Autoimmune Disorders
- Cardiovascular Disorders
- Genetic Disorders
- Infectious Diseases
- Metabolic Disorders
- Neuromuscular Disorders
- Oncological Disorders
- Ophthalmic Disorders
- Other Therapeutic Areas
Size of manufacturer
- Small
- Mid-sized
- Large
Key Geographical Region
- North America
- Europe
- Asia-Pacific and Rest of the World
Transcripts of interviews held with the following senior level representatives of stakeholder companies
- Joachim Bertram (Chief Scientific Officer and Managing Director, IBA Lifesciences)
- Tobias Pohlmann (Founder and Managing Director, BianoScience)
Key companies covered in the report
- Agilent Technologies
- Ajinomoto Bio-Pharma Services
- BioSpring
- CordenPharma
- Integrated DNA Technologies
- Kaneka Eurogentec
- LGC Biosearch Technologies
- Microsynth
- Nitto Denko Avecia
- Sigma Aldrich
- Thermo Fisher Scientific
- Trilink Biotechnologies
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/oligonucleotide-synthesis/304.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Neoantigen Targeted Therapies Market is Expected to Reach 3 billion by 2030
Advances in bioinformatics and genomic data analysis have enabled the identification of cancer antigens that are generally overlooked during immune surveillance; these neoantigens have been shown to possess substantial therapeutic potential
Roots Analysis is pleased to announce the publication of its recent study, titled, “Neoantigen Targeted Therapies Market, 2019-2030.”
The report features an extensive study of the current market landscape, offering an informed opinion on the likely adoption of these therapeutics over the next decade. It features an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain. In addition to other elements, the study includes:
• A detailed assessment of the current market landscape of developers engaged in the development of neoantigen targeted therapies.
• Detailed profiles of developers of neoantigen targeted therapies (shortlisted on the basis of the number of pipeline products).
• A detailed publication analysis of close to 300 peer-reviewed, scientific articles published during the period 2015-2019 (till February), highlighting the research focus within the industry.
• An in-depth analysis of the various patents that have been filed / granted related to neoantigens.
• An analysis of the various partnerships pertaining to neoantigen targeting therapies.
• An analysis of the investments made at various stages of development in companies that are focused on developing neoantigen targeted therapies.
A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
Target Disease Indication
• Bone and Cartilage Cancer
• Colorectal Cancer
• Head and Neck Cancer
• Renal Carcinoma
• Hepatocellular Carcinoma
• Lung Cancer
• Gynecological Cancer
• Others
Type of Treatment
• Personalized
• Off-the-shelf
Type of Immunotherapy
• Dendritic Cell Vaccine
• DNA / RNA-based Vaccine
• Protein / Peptide-based Vaccine
• TIL-based Therapy
Route of Administration
• Intradermal
• Intravenous
• Subcutaneous
• Others
Key Geographical Region
• North America (US)
• Europe (UK, Germany, France, Italy, and Spain
• Rest of the World
Transcripts of interviews held with the following senior level representatives of stakeholder companies:
• Gabriel Nistor, Chief Scientific Officer, AIVITA Biomedical
• Ella Sorani, Vice President Research and Development, BioLineRx
• Heinz Lubenau, Chief Operating Officer and Co-Founder, VAXIMM
Key companies covered in the report
• Bavarian Nordic
• Genocea Biosciences
• Gradalis
• Immunicum
• Immunovative Therapies
• Iovance Biotherapeutics
• Medigene
• Neon Therapeutics
• Precision Biologics
• Vaxon Biotech
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/neoantigen-targeted-therapies-market-2019-2030/257.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
In Silico Drug Discovery Services Market is Expected to Reach 124 billion by 2030
Excessive capital requirement and myriad of other complexities associated with the discovery of biologics have prompted drug developers to adopt in silico tools / techniques to expedite the discovery timelines
Roots Analysis is pleased to announce the publication of its recent study, titled, “In Silico / Computer-Aided Drug Discovery Services Market: Focus on Large Molecules (Antibodies, Proteins, Peptides, Nucleic Acid, Gene Therapy and Vectors), 2020-2030 (Including Structure Based Drug Discovery, Fragment Based Drug Discovery, Ligand Based Drug Discovery, Target Based Drug Discovery / Multi-Target Drug Design, Interface Based Drug Discovery, Approaches).”
The report features an extensive study on the current landscape and the likely future potential of the companies offering services for the discovery of large molecule drugs based on the use of in silico tools and techniques. The study features an in-depth analysis, highlighting the capabilities of various industry stakeholders. In addition to other elements, the report includes:
• A detailed assessment of the current market landscape of companies offering in silico drug discovery services for large molecules.
• Elaborate profiles of key industry players that offer a wide range of in silico drug discovery services (shortlisted on the basis of the company size).
• A detailed peer group-based benchmarking analysis, comparing the involved players based on several relevant parameters related to company and services.
• An insightful competitiveness analysis featuring a four-dimensional bubble chart, highlighting the key players in this domain.
• A detailed analysis assessing the current opportunity within in silico drug discovery services market.
• A discussion on the various business strategies that can be adopted by in silico drug discovery service providers in order to maintain a competitive edge in this industry.
• An insightful analysis highlighting the cost saving potential associated with the use of in silico approaches in the drug discovery process.
• A case study comparing the key challenges associated with the discovery and production of large molecules.
• Insights from an industry-wide survey, featuring inputs solicited from various experts in this domain.
• A discussion on the upcoming computational approaches that are being adopted for drug discovery purposes.
• A case study highlighting several non-computational methods / technologies used in drug discovery process.
A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
Key Drug Discovery Steps
• Target Identification
• Target Validation
• Hit Generation
• Hit-to-Lead
• Lead Optimization
Type of Large Molecule
• Antibodies
• Proteins
• Peptides
• Nucleic Acids
• Vectors
Company Size
• Small
• Mid-sized
• Large
Target therapeutic Area
• Autoimmune Disorders
• Blood Disorders
• Cardiovascular Disorders
• Gastrointestinal and Digestive Disorders
• Hormonal Disorders
• Human Immunodeficiency Virus (HIV) / Acquired Immunodeficiency Syndrome (AIDS)
• Infectious Diseases
• Metabolic Disorders
• Mental Disorders
• Musculoskeletal Disorders
• Neurological Disorders
• Oncological Disorders
• Respiratory Disorders
• Skin Disorders
• Urogenital Disorders
• Others
Type of Sponsor
• Industry Players
• Non-Industry Players
Key Geographical Regions
• North America
• Europe
• Asia-Pacific
Transcripts of interviews held with the following senior level representatives of stakeholder companies
• John L Kulp (Chief Executive Officer and Chief Technical Officer, Conifer Point Pharmaceuticals)
• Sven Benson (Founder, candidum)
• Mark Whittaker (Senior Vice President, Evotec)
• Edelmiro Moman (Scientific Consultant and Teacher, ProSciens)
Key companies covered in the report
• Abzena
• BioDuro
• BioNTech
• ChemPartner
• Creative Biostructure
• GenScript
• LakePharma
• Sundia MediTech
• Sygnature Discovery
• Viva Biotech
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/in-silico-drug-discovery/298.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
In Silico Drug Discovery Services Market is Expected to Reach 124 billion by 2030
Excessive capital requirement and myriad of other complexities associated with the discovery of biologics have prompted drug developers to adopt in silico tools / techniques to expedite the discovery timelines
Roots Analysis is pleased to announce the publication of its recent study, titled, “In Silico / Computer-Aided Drug Discovery Services Market: Focus on Large Molecules (Antibodies, Proteins, Peptides, Nucleic Acid, Gene Therapy and Vectors), 2020-2030 (Including Structure Based Drug Discovery, Fragment Based Drug Discovery, Ligand Based Drug Discovery, Target Based Drug Discovery / Multi-Target Drug Design, Interface Based Drug Discovery, Approaches).”
The report features an extensive study on the current landscape and the likely future potential of the companies offering services for the discovery of large molecule drugs based on the use of in silico tools and techniques. The study features an in-depth analysis, highlighting the capabilities of various industry stakeholders. In addition to other elements, the report includes:
• A detailed assessment of the current market landscape of companies offering in silico drug discovery services for large molecules.
• Elaborate profiles of key industry players that offer a wide range of in silico drug discovery services (shortlisted on the basis of the company size).
• A detailed peer group-based benchmarking analysis, comparing the involved players based on several relevant parameters related to company and services.
• An insightful competitiveness analysis featuring a four-dimensional bubble chart, highlighting the key players in this domain.
• A detailed analysis assessing the current opportunity within in silico drug discovery services market.
• A discussion on the various business strategies that can be adopted by in silico drug discovery service providers in order to maintain a competitive edge in this industry.
• An insightful analysis highlighting the cost saving potential associated with the use of in silico approaches in the drug discovery process.
• A case study comparing the key challenges associated with the discovery and production of large molecules.
• Insights from an industry-wide survey, featuring inputs solicited from various experts in this domain.
• A discussion on the upcoming computational approaches that are being adopted for drug discovery purposes.
• A case study highlighting several non-computational methods / technologies used in drug discovery process.
A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
Key Drug Discovery Steps
• Target Identification
• Target Validation
• Hit Generation
• Hit-to-Lead
• Lead Optimization
Type of Large Molecule
• Antibodies
• Proteins
• Peptides
• Nucleic Acids
• Vectors
Company Size
• Small
• Mid-sized
• Large
Target therapeutic Area
• Autoimmune Disorders
• Blood Disorders
• Cardiovascular Disorders
• Gastrointestinal and Digestive Disorders
• Hormonal Disorders
• Human Immunodeficiency Virus (HIV) / Acquired Immunodeficiency Syndrome (AIDS)
• Infectious Diseases
• Metabolic Disorders
• Mental Disorders
• Musculoskeletal Disorders
• Neurological Disorders
• Oncological Disorders
• Respiratory Disorders
• Skin Disorders
• Urogenital Disorders
• Others
Type of Sponsor
• Industry Players
• Non-Industry Players
Key Geographical Regions
• North America
• Europe
• Asia-Pacific
Transcripts of interviews held with the following senior level representatives of stakeholder companies
• John L Kulp (Chief Executive Officer and Chief Technical Officer, Conifer Point Pharmaceuticals)
• Sven Benson (Founder, candidum)
• Mark Whittaker (Senior Vice President, Evotec)
• Edelmiro Moman (Scientific Consultant and Teacher, ProSciens)
Key companies covered in the report
• Abzena
• BioDuro
• BioNTech
• ChemPartner
• Creative Biostructure
• GenScript
• LakePharma
• Sundia MediTech
• Sygnature Discovery
• Viva Biotech
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/in-silico-drug-discovery/298.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
Human Microbiome-based Products Market is Expected to Grow at a CAGR 40% by 2030
Over the years, extensive R&D efforts have enabled microbiome-based therapy / diagnostic developers to make significant strides, in terms of progressing proprietary product candidates into the clinic.
Roots Analysis has announced the addition of “Human Microbiome Market, 2019-2030” report to its list of offerings
The report features an in-depth analysis, highlighting the diverse capabilities of stakeholders engaged in this domain. In addition to other elements, the study includes:
• A detailed assessment of the current market landscape of microbiome therapeutics, providing information on drug / therapy developer(s).
• Elaborate profiles of key players (established after 2005) that are engaged in the development of microbiome therapeutics.
• A detailed review of the current market landscape of microbiome diagnostic tests, brief profiles of popular diagnostic developers and indicative list of screening and profiling test kits.
• A detailed assessment of the current market landscape of FMT therapies, a geographical clinical trial analysis and information on various stool banks.
• A detailed business portfolio analysis based on an attractiveness and competitiveness (AC) framework.
• An analysis of the varied microbiome-focused initiatives of big pharma players.
• An analysis of the start-ups / small-sized players engaged in the development of microbiome therapeutics and diagnostics.
• An assessment of the most commonly targeted therapeutic indications and details of microbiome-based drugs.
• An analysis of the investments made at various stages of development in start-ups / small-sized companies.
• An indicative list of contract manufacturers, in-house manufacturers and CROs that currently claim to have the necessary capabilities.
• An assessment of the emerging role of big data highlighting efforts focused on the development and implementation of various algorithms / tools to analyze data generated from in the microbiome research.
• An informative case study on the various other applications of microbiome products, such as agriculture, animal health, plant health, food products
A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
Type of Therapy (Tx)
• Prescription Drug
• Prebiotics
• Probiotics
Type of Molecule (Tx)
• Small Molecules
• Biologics
Target Indication (Tx+Dx)
• Acne Vulgaris
• Atopic Dermatitis
• Clostridium difficile Infection
• Colorectal Cancer
• Crohn’s Disease
• Diabetes
• Irritable Bowel Syndrome
• Lactose Intolerance
• Lung Cancer
• Nonalcoholic steatohepatitis (NASH)
• Obesity
• Ulcerative colitis
Therapeutic Area (Tx+Dx)
• Autoimmune Disorders
• Dental Disorders
• Digestive and Gastrointestinal Disorders
• Dermatological Disorders
• Infectious Disease
• Metabolic Disorders
• Oncology
• Others
Key Geographical Regions (Tx+Dx)
• North America
• Europe
• Asia-Pacific and Rest of the World
Key companies covered in the report
• 4D Pharma
• Armata Pharmaceuticals
• Evelo Biosciences
• Rebiotix (Acquired by Ferring Pharmaceuticals)
• Seres Therapeutics
• Vedanta Biosciences
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/human-microbiome-market/281.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
Cell Therapy Manufacturing Market is Projected to Reach USD 11 billion by 2030
Owing to various reasons, the demand for cell therapies is anticipated to increase over the coming years. Therefore, both therapy developers and contract service providers may need to strengthen their capabilities and expand available capacity. In this context, automation is expected to be a key enabler within the cell therapy manufacturing and contract services industry
The USD 11 billion (by 2030) financial opportunity within the Cell Therapy Manufacturing Market has been analyzed across the following segments:
Market Key Players:
Type of therapy
- T-cell therapies (CAR-T therapies, TCR therapies, TIL therapies)
- Dendritic cell therapies
- Tumor cell therapies
- NK cell therapies
- Stem cell therapies
Source of cells
- Autologous
- Allogeneic
Scale of operation
- Clinical
- Commercial
Purpose of manufacturing
- Contract manufacturing
- In-house manufacturing
Key geographical regions
- North America
- Europe
- Asia Pacific
- Rest of the world
Read Detailed Analysis: https://www.rootsanalysis.com/reports/view_document/cell-therapy-manufacturing/285.html
The Cell Therapy Manufacturing Market (3rd Edition), 2019 - 2030 report features the following companies, which we identified to be key players in this domain:
Market Key Players:
- BioNTech Innovative Manufacturing Services
- Cell Therapies
- Cell and Gene Therapy Catapult
- Center for Cell and Gene Therapy, Baylor College of Medicine
- Centre for Cell Manufacturing Ireland, National University of Ireland
- Clinical Cell and Vaccine Production Facility, University of Pennsylvania
- Cognate BioServices
- FUJIFILM
- Guy’s and St. Thomas’ GMP Facility, Guy’s Hospital
- Hitachi Chemical
- KBI Biopharma
- Laboratory for Cell and Gene Medicine, Stanford University
- Lonza
- MaSTherCell
- MEDINET
- Molecular and Cellular Therapeutics, University of Minnesota
- Newcastle Cellular Therapies Facility, Newcastle University
- Nikon CeLL innovation
- Rayne Cell Therapy Suite, King’s College London
- Roslin Cell Therapies
- Scottish National Blood Transfusion Services Cellular Therapy Facility, Scottish Centre for Regenerative Medicine
- Sydney Cell and Gene Therapy
- WuXi Advanced Therapies
Table of Contents
- Preface
- Executive Summary
- Introduction
- Market Overview
- Regulatory Landscape
- Roadmaps for Overcoming Existing Challenges
- Automation Technologies for Cell Therapy Manufacturing
- Profiles: Industry Players
- Profiles: Non-Industry Players
- Role of Non-Profit Organizations
- Partnerships
- Facility Expansions
- Capacity Analysis
- Demand Analysis
- Cost Price Analysis
- Make Versus Buy Decision Making Framework
- Market Sizing and Opportunity Analysis
- Key Insights
- SWOT Analysis
- Conclusion
- Survey Analysis
- Interview Transcripts
- Appendix 1: Tabulated Data
- Appendix 2: List of Companies and Organizations
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/cell-therapy-manufacturing/285.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Biopharmaceutical Contract Manufacturing Market Size, Analysis, Opportunities and Trends 2019 –2030
Roots Analysis has done a detailed study on Biopharma Contract Manufacturing Market (3rd Edition), 2019-2030, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Market Insights
- A detailed review of the overall landscape of the biopharmaceutical contract manufacturing market, featuring a comprehensive list of active CMOs and detailed analysis of the manufacturing service providers based on a number of parameters, such as scale of operation (preclinical, clinical and commercial), type of biologics manufactured (peptides / proteins, antibodies, vaccines, cell therapies, gene therapies, antibody drug conjugates, vectors, biosimilars, nucleic acids and others), type of expression systems used (mammalian, microbial and others), year of establishment, employee size, geographical location of the CMO, number of manufacturing facilities, as well as the location of these facilities, GMP compliance, affiliations to regulatory agencies, type of bioreactors used (single-use bioreactors and stainless steel bioreactors), mode of operation of bioreactors (batch, fed-batch and perfusion) and bioprocessing capacity.
- Elaborate profiles of key players that have a diverse range of capabilities for the development, manufacturing and packaging of biologics. Each profile provides an overview of the company, its financial performance (if available), information related to its service portfolio, manufacturing facilities, and details on partnerships, recent developments (expansions), as well as a comprehensive future outlook.
- A detailed discussion on the key enablers in this domain, including certain niche product classes, such as antibody drug conjugates (ADCs), bispecific antibodies, cell therapies, gene therapies and viral vectors, which are likely to have a significant impact on the growth of the contract services market.
- A case study on the growing global biosimilars market, highlighting the opportunities for biopharmaceutical CMOs and CDMOs.
- A case study comparing the key characteristics of large molecule and small molecule drugs, along with details on the various steps involved in their respective manufacturing processes.
- A discussion on challenges related to in-house manufacturing, featuring a brief overview of the various parameters that a drug / therapy developer may need to take into consideration while deciding whether to manufacture its products in-house or outsource.
- An analysis of the recent collaborations (signed since 2013) focused on the contract manufacturing of biologics; the analysis is based on various parameters, such as the year in which the agreement was signed, type of agreement, focus area and type of biologics.
- A detailed analysis of the various mergers and acquisitions that have taken place in this domain, highlighting the trend in the number of companies acquired between 2013-2018, along with the geographical distribution of this activity. The analysis also depicts the relationship between important deal multiples based on the revenue, number of employees and experience of the acquired company.
- An analysis on the recent trends within biopharmaceutical contract manufacturing industry, highlighting various facility and capability expansions. In addition, it provides information on the technology advancements related to biomanufacturing.
- A detailed capacity analysis, taking into consideration the individual development and manufacturing capacities of various stakeholders (small-sized, mid-sized, large and very large CMOs / CDMOs) in the market, using data from both secondary and primary research. The study examines the distribution of global biopharmaceutical manufacturing capacity by scale of operation (preclinical / clinical, commercial), size of company (small-sized, mid-sized, large and very large), and geography (North America (the US and Canada), Europe (Italy, Germany, France, Spain, the UK and rest of Europe), Asia and Middle East (China, India, Japan, South Korea and rest of the Asia and Middle East), and rest of the world (including Australia).
- An informed estimate of the annual demand for biologics, taking into account the top 20 biologics, based on a various relevant parameter, such as target patient population, dosing frequency and dose strength of the abovementioned products.
- A discussion on affiliated trends, key drivers and challenges, under a comprehensive SWOT framework, which are likely to impact the industry’s evolution, including a Harvey ball analysis, highlighting the relative effect of each SWOT parameter on the overall pharmaceutical industry.
- A survey analysis featuring inputs solicited from various experts who are directly / indirectly involved in providing CMO services to medical device developers.
Read Detailed Analysis: https://www.rootsanalysis.com/reports/view_document/biopharma-contract-manufacturing-market-3rd-edition-2019-2030/250.html
The report also features the likely distribution of the current and forecasted opportunity across important market segments, mentioned below:
Commonly Outsourced Business Operations
- Active Pharmaceutical Ingredients (API)
- Finished Dosage Formulations (FDF)
Types of Expression System
- Mammalian
- Microbial
- Others
Company Size
- Small
- Mid-Sized
- Large and Very Large
Scale of Operation
- Preclinical
- Clinical
- Commercial
Key Geographical Region
- North America
- Europe
- Asia-Pacific
For more information, please click on the following link:
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Antibody Contract Manufacturing Market 2019 Glob.al Share, Trend, Segmentation and Forecast to 2030
Roots Analysis has done a detailed study on Antibody Contract Manufacturing Market, 2020-2030, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
Key Inclusions
• A detailed review of the overall landscape of companies, offering contract services for the manufacturing of antibodies, along with information on year of establishment, company size, scale of operation (preclinical, clinical and commercial), location of headquarters, number of manufacturing facilities and location of these facilities, type of antibody manufactured (monoclonal antibodies, bispecific antibodies and polyclonal antibodies), type of expression systems used (mammalian, microbial and others), fill / finish operations and affiliations to regulatory agencies.
• A competitiveness analysis of key players engaged in this domain, featuring an assessment based on their supplier strength (related to the experience of a contract manufacturer), and service strength (which takes into account the size of service portfolio and scale of operation).
• A benchmark analysis, highlighting the key focus areas of small, mid-sized and large companies, comparing their existing capabilities within and beyond their respective (geography-based) peer groups.
• An analysis of the various partnerships pertaining to contract manufacturing of antibodies, which have been established since 2013, based on several parameters, such as the year of agreement, type of partnership, project scale and focus therapeutic area.
• An analysis of the various expansion initiatives undertaken by service providers, in order to augment their respective antibody manufacturing capabilities, over the period 2017-2019 (till October), taking into consideration parameters, such as year of expansion, type of expansion (capacity expansion, facility expansion and new facility), type of antibodies manufactured and location of manufacturing facility.
• An estimate of the overall, installed capacity for manufacturing antibodies based on data reported by industry stakeholders in the public domain; it highlights the distribution of available antibody production capacity on the basis of company size (small, mid-sized, large and very large firms), scale of operation (preclinical, clinical and commercial), and key geographical regions (North America, Europe, Asia).
• Informed estimates of the annual commercial and clinical demand for antibodies, based on various relevant parameters, such as target patient population, dosing frequency and dose strength.
• Elaborate profiles of the key industry players that offer contract manufacturing services at all scales of operation and have more than two manufacturing facilities. Each profile features a brief overview of the company, information on its service portfolio, details related to its manufacturing capabilities and facilities, and an informed future outlook.
• A case study comparing the key characteristics of large molecule and small molecule drugs, along with details on the various steps and challenges involved in their respective manufacturing processes.
• A discussion on affiliated trends, key drivers and challenges, under a SWOT framework, which are likely to impact the industry’s evolution, including a Harvey ball analysis, highlighting the relative effect of each SWOT parameter on the overall pharmaceutical industry.
Read Detailed Analysis: https://www.rootsanalysis.com/reports/view_document/antibody-cmo-market/295.html
The report also features the likely distribution of the current and forecasted opportunity across important market segments, mentioned below:
Type of Antibodies
• Monoclonal Antibodies
• Bispecific Antibodies
• ADCs
• Others
Company Size
• Small
• Mid-sized
• Large / Very Large
Scale of Operation
• Preclinical / Clinical
• Commercial
Type of expression system used
• Mammalian
• Microbial
Key geographical regions
• North America
• Europe
• Asia and RoW
The report includes detailed transcripts of discussions held with the following experts:
• Dietmar Katinger (Chief Executive Officer, Polymun Scientific)
• David C Cunningham (Director, Corporate Development, Goodwin Biotechnology)
• Claire Otjes (Marketing Manager, Batavia Biosciences)
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/antibody-cmo-market/295.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
Next Generation Immune Checkpoint Modulators Market Report – Industry Size, Share, Trends, Growth and Forecast Till 2030
Over time, significant strides have been made in immune checkpoint research, resulting in the discovery of several inhibitory (LAG-3, TIM-3, TIGIT, VISTA and B7-H3) and stimulatory receptors (OX40, ICOS, GITR, 4-1BB and CD40), which are being investigated as potential targets for therapy development. Further, studies of combinatorial immune checkpoint blockade / co-stimulation, targeting newly identified checkpoints along with known checkpoint inhibitor therapies, have demonstrated promising clinical outcomes as well.
The USD 12 billion (by 2030) financial opportunity within the Next Generation Immune Checkpoint Modulators Market has been analyzed across the following segments:
Target Disease Indication
• Breast Cancer
• Chronic Lymphocytic Leukemia
• Colorectal Cancer
• Head and Neck Cancer
• Lung Cancer
• Lupus Nephritis
• Melanoma
• Multiple Myeloma
• Primary Sjögren's Syndrome
• Others
Target Immune Checkpoint
• B7-H3
• CD38
• CD40
• CD47
• Others
Mechanism of Action
• Inhibitory
• Stimulatory
Therapeutic Modality
• Monoclonal Antibody
• Small Molecule
• Type of Therapy
• Monotherapy
• Combination Therapy
• Route of Administration
• Intravenous
• Subcutaneous
• Others
Key Geographical Regions
• North America
• Europe
• Asia-Pacific and the Rest of the World
Read Detailed Analysis: https://www.rootsanalysis.com/reports/view_document/immune-checkpoint-inhibitors/303.html
The Next Generation Immune Checkpoint Inhibitors and Stimulators Market, 2020-2030 report features the following companies, which we identified to be key players in this domain:
• Bristol Myers Squibb
• GlaxoSmithKline
• Incyte
• Novartis
• Trillium Therapeutics
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Current Market Landscape: Clinical and Preclinical Molecules
5. Market Landscape: Therapies Targeting Cd47
6. Market Landscape: Therapies Targeting 4-1bb
7. Clinical Trial Analysis
8. Company Profiles: Next Generation Inhibitors and Stimulators
9. Academic Grants Analysis
10. Partnerships and Collaborations
11. Target Competitiveness Analysis
12. Big Pharma Initiatives
13. Market Forecast and Opportunity Analysis
14. Concluding Remarks
15. Executive Insights
16. Appendix 1: Tabulated Data
17. Appendix 2: List of Companies and Organizations
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/immune-checkpoint-inhibitors/303.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
Cell Therapy Manufacturing Market is Expected to Reach 11 billion by 2030
Owing to various reasons, the demand for cell therapies is anticipated to increase over the coming years. Therefore, both therapy developers and contract service providers may need to strengthen their capabilities and expand available capacity. In this context, automation is expected to be a key enabler within the cell therapy manufacturing and contract services industry
The USD 11 billion (by 2030) financial opportunity within the Cell Therapy Manufacturing Market has been analyzed across the following segments:
Market Key Players:
Type of therapy
• T-cell therapies (CAR-T therapies, TCR therapies, TIL therapies)
• Dendritic cell therapies
• Tumor cell therapies
• NK cell therapies
• Stem cell therapies
Source of cells
• Autologous
• Allogeneic
Scale of operation
• Clinical
• Commercial
Purpose of manufacturing
• Contract manufacturing
• In-house manufacturing
Key geographical regions
• North America
• Europe
• Asia Pacific
• Rest of the world
Read Detailed Analysis: https://www.rootsanalysis.com/reports/view_document/cell-therapy-manufacturing/285.html
The Cell Therapy Manufacturing Market (3rd Edition), 2019 - 2030 report features the following companies, which we identified to be key players in this domain:
Market Key Players:
• BioNTech Innovative Manufacturing Services
• Cell Therapies
• Cell and Gene Therapy Catapult
• Center for Cell and Gene Therapy, Baylor College of Medicine
• Centre for Cell Manufacturing Ireland, National University of Ireland
• Clinical Cell and Vaccine Production Facility, University of Pennsylvania
• Cognate BioServices
• FUJIFILM
• Guy’s and St. Thomas’ GMP Facility, Guy’s Hospital
• Hitachi Chemical
• KBI Biopharma
• Laboratory for Cell and Gene Medicine, Stanford University
• Lonza
• MaSTherCell
• MEDINET
• Molecular and Cellular Therapeutics, University of Minnesota
• Newcastle Cellular Therapies Facility, Newcastle University
• Nikon CeLL innovation
• Rayne Cell Therapy Suite, King’s College London
• Roslin Cell Therapies
• Scottish National Blood Transfusion Services Cellular Therapy Facility, Scottish Centre for Regenerative Medicine
• Sydney Cell and Gene Therapy
• WuXi Advanced Therapies
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Market Overview
5. Regulatory Landscape
6. Roadmaps for Overcoming Existing Challenges
7. Automation Technologies for Cell Therapy Manufacturing
8. Profiles: Industry Players
9. Profiles: Non-Industry Players
10. Role of Non-Profit Organizations
11. Partnerships
12. Facility Expansions
13. Capacity Analysis
14. Demand Analysis
15. Cost Price Analysis
16. Make Versus Buy Decision Making Framework
17. Market Sizing and Opportunity Analysis
18. Key Insights
19. SWOT Analysis
20. Conclusion
21. Survey Analysis
22. Interview Transcripts
23. Appendix 1: Tabulated Data
24. Appendix 2: List of Companies and Organizations
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/cell-therapy-manufacturing/285.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
Biopharmaceutical Manufacturing Market Analysis, opportunities Trends and Industry Strategies 2019 – 2030
Owing to the ever-increasing number of start-ups that are involved in R&D of novel biologics, there is an enormous opportunity for the CMOs in this domain. It is worth emphasizing that, since 2000, more than 115 new CMOs have been established in order to serve to the growing demand for novel biologics that have specific manufacturing requirements. The contemporary contract services market features a mix of large and small-sized CMOs and is characterized by multiple mergers and acquisitions as stakeholders strive to broaden their respective service portfolios.
This has enabled several CMOs to offer end-to-end services, ranging from drug development, including preliminary R&D, preclinical and clinical trials, to commercial scale production and regulatory filings
The USD 13.9 billion (by 2030) financial opportunity within the Biopharmaceutical Manufacturing Market has been analysed across the following segments:
Key Players:
Commonly Outsourced Business Operations
• Active Pharmaceutical Ingredients (API)
• Finished Dosage Formulations (FDF)
Types of Expression System
• Mammalian
• Microbial
• Others
Company Size
• Small
• Mid-Sized
• Large and Very Large
Scale of Operation
• Preclinical
• Clinical
• Commercial
Key Geographical Region
• North America
• Europe
• Asia-Pacific
• Rest of the World
Read Detailed Analysis: https://www.rootsanalysis.com/reports/view_document/biopharma-contract-manufacturing-market-3rd-edition-2019-2030/250.html
The Biopharma Contract Manufacturing Market (3rd Edition), 2019-2030. report features the following companies, which we identified to be key players in this domain:
Market Key Players:
• 3P Biopharmaceuticals
• Abzena
• Albany Molecular Research
• BioVectra
• BioXcellence (Boehringer Ingelheim)
• Celonic
• Charles River Laboratories
• ChemPartner
• Cobra Biologics
• CordenPharma
• Cytovance Biologics
• GE Healthcare
• Goodwin Biotechnology
• Grand River Aseptic Manufacturing
• IDT Biologika
• KBI BioPharma
• Kemwell Biopharma
• LFB Biomanufacturing
• Meridian Life Science
• Patheon
• Pfizer CentreOne
• PX'Therapeutics
• Samsung BioLogics
• Sanofi, CEPiA
• Thermo Fisher Scientific
• Vetter Pharma International
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Competitive Landscape
5. Biopharmaceutical Contract Manufacturing in North America
6. Biopharmaceutical Contract Manufacturing in Europe
7. Biopharmaceutical Contract Manufacturing in Asia Pacific And the Rest of The World
8. Biopharmaceutical Contract Manufacturing in Asia Pacific And the Rest of The World
9. Case Study: Outsourcing of Biosimilars
10. Case Study: Comparison of Small Molecule and Large Molecule Drugs / Therapies
11. Case Study on In-House Manufacturing
12. Collaborations
13. Recent Developments
14. Capacity Analysis
15. Demand Analysis
16. Market Forecast
17. SWOT Analysis
18. Future of The Biopharmaceutical CMO Market
19. Survey Analysis
20. Interview Transcripts
21. Appendix 1: List of Non-Industry Players
22. Appendix 1: List of Non-Industry Players
23. Appendix 3: List of Companies and Organizations
For more information, please click on the following link:
https://www.rootsanalysis.com/reports/view_document/biopharma-contract-manufacturing-market-3rd-edition-2019-2030/250.html
About Roots Analysis
Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com
Contact Information
Roots Analysis Private Limited
Gaurav Chaudhary
+1 (415) 800 3415
Gaurav.Chaudhary@rootsanalysis.com
